Brothers for Life is a National Campaign targeting men over the age of 30. The initiative has been initiated by Johns Hopkins Health and Education in South Africa (JHHESA), Sonke Gender Justice (Sonke), South African National Aids Council (SANAC) and other key stakeholders. It is aimed at addressing the risks associated with having multiple and concurrent partnerships, men’s limited involvement in fatherhood, lack of knowledge of HIV status by many, low levels of testing and disclosure, and insufficient health seeking behaviours in general.

This project is demonstrating the impact of involving men in child protection and violence prevention activities in KZN and the Eastern Cape.

Crucial to the success of Sonke's work is ensuring a central role for those most directly affected by violence and HIV. A platform is required for their voices to inform our efforts and be represented across Sonke activities.

Sonke launched the One Man Can Campaign in November 2006. It is now being implemented in eight of South Africa's nine provinces, and in Burundi, Kenya, Malawi, Mozambique, Namibia and Uganda.

PhotoVoice is a school-based project that trains learners to use photography and writing to chronicle their daily lives, provides a look at the community through its children’s eyes.

With support from UNICEF, Sonke has been working in KwaZulu-Natal and the Eastern Cape since late 2006 to promote greater involvement by men in meeting the needs of children affected by HIV and AIDS. Alongside community education and capacity building for local partners, Sonke has used PhotoVoice to help children convey their experiences, needs and aspirations and to mobilize adults — and especially men — to meet their needs.

Sonke Gender Justice is helping to build government's capacity to implement initiatives that promote gender equality, empower women and engage men.

The Sonke Gender Justice Network is working in prisons in the Western Cape to reduce new HIV infections and increase positive living amongst staff and inmates both while in prison and upon release.

The Red Card Project is a joint campaign by Sonke Gender Justice Network and Grassroot Soccer to prevent child sexual exploitation in Southern Africa during and after the 2010 FIFA World Cup. This project is funded mainly by the Oak Foundation.

Work with refugees and migrants is one of Sonke's priorities.

Sonke Gender Justice is involved in a number of research initiatives examining different aspects of gender violence and HIV/AIDS, including research into the impact of PEPFAR funding on HIV/AIDS organisations in Southern Africa, South African men's perceptions around violence against women, and research into male circumcision.

Sonke Gender Justice Network has been actively involved in efforts to stem the xenophobic violence and its aftermath in South Africa.